MARBOMET

Third-Generation Fluoroquinolone Antibiotic
Ceftriaxone and Tazobactam Potentiated Antibiotic
Antibiotic
Dog & Cat
Tablet

Composition

Each coated tablet contains:
Marbofloxacin. 50 mg

Each coated tablet contains:
Marbofloxacin. 150 mg

Indications

Treatment of severe and recurrent urinary tract infections (UTIs).
Management of deep, complicated skin and soft tissue infections (e.g., pyoderma).
Therapy for respiratory tract infections caused by susceptible organisms.
Treatment of infections where resistance to first-line antibiotics is confirmed or suspected.
Effective for deep-seated infections due to excellent tissue penetration (e.g., bone).

Mechanism of Action

Marbofloxacin is a bactericidal agent that targets the bacterial DNA replication process. It selectively inhibits two critical bacterial enzymes: DNA gyrase and Topoisomerase IV. DNA gyrase is necessary for unwinding and supercoiling the bacterial chromosome for replication, while Topoisomerase IV separates the newly copied DNA. By blocking these enzymes, the drug prevents DNA replication, transcription, and repair, leading to the rapid and irreversible death of the bacterial cell. This mechanism provides high efficacy against many Gram-negative and Gram-positive pathogens.

Benefits

Broad-spectrum efficacy against hard-to-treat bacterial pathogens.
Rapid absorption and high bioavailability ensure quick therapeutic levels.
Excellent penetration into tissues, including skin, prostate, and bone.
Often provides effective treatment for multi-drug resistant infections.
strength simplifies dosing for medium and large dogs.

Usage & Recommendation

Dogs
General Use: 2 -5 mgmg / Kg body weight, administered once daily (SID).
Note: Treatment duration varies based on the type and severity of the infection.
Marbomet 50 mg : Dog up to 10 Kg B.wt
Marbomet 150 mg: Dog from 20-30 Kg B.wt:

Presentation

Marbomet 150: strip of 10 Tablets
Marbomet 50 mg: Strip of 5 tablets

Dosage

Tablet

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south America

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