NYZOM INJ

Each sachet contains:
lsometamidium Chloride Hydrochloride. 1 gm

Curative treatment of active Trypanosomiasis (e.g., Surra, Nagana).
Long-term prophylactic protection against Trypanosomiasis in endemic zones.
Used for animals being moved into or through high-risk tsetse fly areas.
Management of anemia and systemic debility caused by trypanosomal infections.
Crucial for disease control in breeding and production herds.

Isometamidium is a cationic trypanocide that works by strongly binding to the DNA of the Trypanosoma parasite. It primarily targets the parasite's kinetoplast DNA, intercalating into its structure. This interference halts the replication and transcription processes essential for the parasite's division and survival, leading to rapid parasite death. The compound's characteristic slow release from the injection site and binding to tissue provide a sustained concentration in the bloodstream, conferring prophylactic (preventative) immunity for several months.

High-dose concentration simplifies dosing for large animals.
Provides long duration of prophylactic protection (up to 4 months).
Highly effective for both mass treatment and long-term prevention.
Reduces overall morbidity and mortality rates in high-risk environments.
Convenient pre-measured 1-gram dose in sachet form for reconstitution.

Cattle (Curative): 0.25 - 0.5 mg/kg body weight
Deep Intramuscular (I.M.) injection.Cattle (Prophylactic)
0.5 - 1.0 mg/kg body weight
Deep Intramuscular (I.M.) injection.
Typically dissolved in 20 ml of sterile water per 1 gm sachet to make a 5% w/v solution.
Follow the specific directions on the pack carefully for solvent volume.

Box of 10 sachets of 2.37 g
Box of 10 sachets of 23.7 g

Injection