NYZOM

Each sachet & vial contains:
lsometamidium Chloride Hydrochloride. 125 mg

Curative treatment of Trypanosomiasis (e.g., Surra, Nagana) in livestock.
Long-term prophylactic protection against Trypanosomiasis in endemic areas.
Used for animals being moved into or through tsetse fly-infested zones.
Management of severe anemia and debility caused by trypanosomes.
Controls the spread of the disease within the herd/flock.

Isometamidium acts as a cationic compound, exhibiting high affinity for the DNA of the Trypanosoma parasites. It intercalates (inserts itself) into the parasite's kinetoplast DNA, specifically preventing DNA replication and transcription, which is essential for the parasite's survival and division. This results in the rapid death of the parasite. Crucially, the compound is slowly released from the injection site and strongly bound to tissues, providing a prolonged concentration in the bloodstream, which is responsible for its effective prophylactic (preventative) action.

Highly effective for both treating clinical cases and preventing new infections.
Provides long duration of protection (up to 4 months) from a single dose.
Reduces morbidity and mortality rates significantly in high-risk zones.
Cost-effective method for sustainable disease control in endemic regions.
Convenient pre-measured dose in sachet form for reconstitution.

Cattle (Curative): 0.25 - 0.5 mg/kg body weight
Deep Intramuscular (I.M.) injection.

Cattle (Prophylactic)
0.5 - 1.0 mg/kg body weight
Deep Intramuscular (I.M.) injection.
Typically dissolved in 5 ml of sterile water per 125 mg sachet to make a 2.5% w/v solution.
Follow the specific directions on the pack carefully.

Box of 10 sachets of 2.37 g
Box of 10 sachets of 23.7 g

Injection